CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012847
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable C-mannosyltransferase DPY19L1 
Protein Synonyms/Alias
 Dpy-19-like protein 1; Protein dpy-19 homolog 1 
Gene Name
 DPY19L1 
Gene Synonyms/Alias
 GA0500; KIAA0877 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
103PLVINTLKRFNLYPEubiquitination[1]
360ILKYLTSKIFGIADDubiquitination[1]
547EWIKYSTKPDAVFAGubiquitination[1]
652PLCNLLVKDSKPHFTubiquitination[2]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Glycosyltransferase; Membrane; Polymorphism; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 675 AA 
Protein Sequence
MEGRPPPEGR PPPRPRTGRA PRGRRRAVFA AVLHWSHITH LFENDRHFSH LSTLEREMAF 60
RTEMGLYYSY FKTIVEAPSF LNGVWMIMND KLTEYPLVIN TLKRFNLYPE VILASWYRIY 120
TKIMDLIGIQ TKICWTVTRG EGLSPIESCE GLGDPACFYV AVIFILNGLM MALFFIYGTY 180
LSGSRLGGLV TVLCFFFNHG ECTRVMWTPP LRESFSYPFL VLQMLLVTHI LRATKLYRGS 240
LIALCISNVF FMLPWQFAQF VLLTQIASLF AVYVVGYIDI CKLRKIIYIH MISLALCFVL 300
MFGNSMLLTS YYASSLVIIW GILAMKPHFL KINVSELSLW VIQGCFWLFG TVILKYLTSK 360
IFGIADDAHI GNLLTSKFFS YKDFDTLLYT CAAEFDFMEK ETPLRYTKTL LLPVVLVVFV 420
AIVRKIISDM WGVLAKQQTH VRKHQFDHGE LVYHALQLLA YTALGILIMR LKLFLTPHMC 480
VMASLICSRQ LFGWLFCKVH PGAIVFAILA AMSIQGSANL QTQWNIVGEF SNLPQEELIE 540
WIKYSTKPDA VFAGAMPTMA SVKLSALRPI VNHPHYEDAG LRARTKIVYS MYSRKAAEEV 600
KRELIKLKVN YYILEESWCV RRSKPGCSMP EIWDVEDPAN AGKTPLCNLL VKDSKPHFTT 660
VFQNSVYKVL EVVKE 675 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW. 
Interpro
 IPR018732; Dpy-19. 
Pfam
 PF10034; Dpy19 
SMART
  
PROSITE
  
PRINTS