CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028659
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GTPase-activating Rap/Ran-GAP domain-like protein 3 
Protein Synonyms/Alias
  
Gene Name
 Garnl3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
377ETPTFAQKRRRTLDMacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 997 AA 
Protein Sequence
MKHFCSSSVS EDLGCRRGDF SRKHYGSVEL LISSDADGAI QRAGRFRVEN GSTDESAAAL 60
PGTWRRTDVH LENPEYHTRW YFKYFLGQVH QNYIGNDAEK SPFFLSVTLS DQNNQRVPQY 120
RAILWRKTGT QKICLPYSPT KTLSVKSILS AMNLDKFEKG PREIFHPEIQ KDLLVLEEQE 180
GSVNFKFGVL FAKDGQLTDD EMFSNEIGSE AFQKFLNLLG DTITLKGWTG YRGGLDTKNN 240
TTGINSVYTV YQGHEVMFHV STMLPYSKEN RQQVERKRHI GNDIVTIVFQ EGEESSPAFK 300
PSMIRSHFTH IFALVRYDQQ NDNYRLKIFS EESVPLFGPP LPSPPVFTDH QEFRDFLLVK 360
LINGEKATLE TPTFAQKRRR TLDMLIRSLY QDLMPDLHKN MLNRRSFSDV LPESPKSARK 420
KEEARQAEFV RIGQALKLKS IVRGDAPSSL AASGMCKKEP WEPQCFCCNF PHEAVCADPW 480
GQALLVSTDA GVLLVDDDLP SVPVFDRTLP VKQIHVLETL DLLVLRADKG KDARLFVFRL 540
SAVQKGLDGR QTGRSRSDCR ENKLEKTKGC HLYAINTHHS RELRIVVAIR NKLLLITRKP 600
HNKPSGVPGV SLLSPLSESP VEEFQYIREI CLCDSPAVMA LVDGPTEESD NLICVAYRHQ 660
FDVVNESTGE AFRLHHVEAN KVNFVAAIDV YEDGEAGLLL CYNYSCIYKK VCPFNGGSFL 720
LQPSASDFQF CWNQAPYAIV CAFPYLLAFT TDSMEIRLVV NGNLVHTAVV PQLQLVASRS 780
DIYFTAATTV HEGSSGGSSK GASAHTSPQT PPARDTPLFP SSLGEGEIQS KNLYKIPLRN 840
LVGRSIERPL KSPLVSKVIT PPTSIGLGVA AIPVTHSLSL SRMEIKEIAS RTRRELLGLS 900
DDGGTKTEGA PRAKSKTRKR LEESQGGPKP ETVRSASSDR IPSGILESPA SEANPEGHNH 960
WASSEQDAGV DKEGSPGSGS SPFQLMASSE EDIIDLK 997 
Gene Ontology
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR001180; Citron.
 IPR000331; Rap_GAP_dom. 
Pfam
 PF00780; CNH
 PF02145; Rap_GAP 
SMART
  
PROSITE
 PS50219; CNH
 PS50085; RAPGAP 
PRINTS