CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025821
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 EBNA-2 co-activator variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
231SHTIRDLKYTIENPRubiquitination[1]
247FVDSHHQKPVNAIIEubiquitination[1]
303EPFAAEAKFFTESRLubiquitination[1]
420KLNSGDYKTIHLSSIubiquitination[1]
569SGDTQKAKQFLPFLQubiquitination[1]
695AERSSYYKSLLSAEEubiquitination[1]
940LNAQESAKSARLNLWubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 964 AA 
Protein Sequence
RCCSCERPAS PSRPPSAAGS QPAPRLDSLS PTPTPTLTPP VRPAAPLVAF ASPHMASSAQ 60
SGGSSGGPAV PTVQRGIIKM VLSGCAIIVR GQPRGGPPPE RQINLSNIRA GNLARRAAAT 120
QPDAKDTPDE PWAFPAREFL RKKLIGKEVC FTIENKTPQG REYGMIYLGK DTNGENIAES 180
LVAEGLATRR EGMRANNPEQ NRLSECEEQA KAAKKGMWSE GNGSHTIRDL KYTIENPRHF 240
VDSHHQKPVN AIIEHVRDGS VVRALLLPDY YLVTVMLSGI KCPTFRREAD GSETPEPFAA 300
EAKFFTESRL LQRDVQIILE SCHNQNILGT ILHPNGNITE LLLKEGFARC VDWSIAVYTR 360
GAEKLRAAER VAKERRLRIW RDYVAPTANL DQKDKQFVAK VMQVLNADAI VVKLNSGDYK 420
TIHLSSIRPP RLEGENTQDK NKKLRPLYDI PYMFEAREFL RKKLIGKKVN VTVDYIRPAS 480
PATETVPAFS ERTCATVTIG GINIAEALVS KGLATVIRYR QDDDQRSSHY DELLAAEARA 540
IKNGKGLHSK KEVPIHRVAD ISGDTQKAKQ FLPFLQRAGR SEAVVEYVFS GSRLKLYLPK 600
ETCLITFLLA GIECPRGARN LPGLVQEGEP FSEEATLFTK ELVLQREVEV EVESMDKAGN 660
FIGWLHIDGA NLSVLLVEHA LSKVHFTAER SSYYKSLLSA EEAAKQKKEK VWAHYEEQPV 720
EEVMPVLEEK ERSASYKPVF VTEITDDLHF YVQDVETGTQ LEKLMENMRN DIASHPPVEG 780
SYAPRRGEFC IAKFVDGEWY RARVEKVESP AKIHVFYIDY GNREVLPSTR LGTLSPAFST 840
RVLPAQATEY AFAFIQVPQD DDARTDAVDS VVRDIQNTQC LLNVEHLSAG CPHVTLQFAD 900
SKGDVGLGLV KEGLVMVEVR KEKQFQKVIT EYLNAQESAK SARLNLWRYG DFRADDADEF 960
GYSR 964 
Gene Ontology
 GO:0016442; C:RNA-induced silencing complex; IEA:InterPro.
 GO:0004518; F:nuclease activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0031047; P:gene silencing by RNA; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR016685; Silence_cplx_Nase-comp_TudorSN.
 IPR016071; Staphylococal_nuclease_OB-fold.
 IPR006021; Staphylococcal_nuclease.
 IPR002071; Thermonucl_AS.
 IPR002999; Tudor. 
Pfam
 PF00565; SNase
 PF00567; TUDOR 
SMART
 SM00318; SNc
 SM00333; TUDOR 
PROSITE
 PS01284; TNASE_2
 PS50830; TNASE_3
 PS50304; TUDOR 
PRINTS