CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017302
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Facilitated trehalose transporter Tret1-2 homolog 
Protein Synonyms/Alias
 DmTret1-2 
Gene Name
 Tret1-2 
Gene Synonyms/Alias
 CG8234 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
262NTCLELFKRNNLKPLacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Fails to transport trehalose. 
Sequence Annotation
 CARBOHYD 182 182 N-linked (GlcNAc...) (Potential).
 CARBOHYD 305 305 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 488 AA 
Protein Sequence
MKILMRADTH VSFSVPADGL KANFTFSQVL AALSVSLCSL VVGFVSAYTS PALVSMTDRT 60
ITSFEVTKDA GSWVGGIMPL AALAGGITGG PLIEYLGRRS TILATAVPFI VSSLLIACAV 120
NVIMILCGRF LTGFCVGIAS LSLPVYLGET LQPEVRGTLG LLPTALGNIG ILVCYVAGSF 180
MNWSMLAFLG AALPVPFLIL MIIIPETPRW FVNRGQEERA RKALKWLRGK EADVEPELKE 240
LMQSQADADR QATQNTCLEL FKRNNLKPLS ISLGLMFFQQ FSGINAVIFY TVQIFKDAGS 300
TIDSNLSTII VGVVNFFATF MGIILIDRLG RKILLYVSDI AMIVTLSILG GFFYCKAHGP 360
DVSHLGWLPL TCFVIYILGF SLGFGPIPWL MMGEILPAKI RGPAASVVTA FNWFCTFVVT 420
KTFQDLTVAM GAHGAFWLFG AICIVGLFFV IIFVPETRGK SLEEIERKMM GRVPMSSVVN 480
IKPFPFNM 488 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0044459; C:plasma membrane part; IDA:UniProtKB.
 GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro. 
Interpro
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR00171; SUGRTRNSPORT.