CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020483
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 COMM domain-containing protein 4 
Protein Synonyms/Alias
  
Gene Name
 Commd4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
50GQGIDYEKILKLTADacetylation[1]
50GQGIDYEKILKLTADubiquitination[2]
59LKLTADAKFESGDVKubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Down-regulates activation of NF-kappa-B (By similarity). 
Sequence Annotation
 DOMAIN 130 199 COMM.  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 199 AA 
Protein Sequence
MRFRFCGDLD CPDWVLAEIS TLAKISSVKL RLLCSQVLKE LLGQGIDYEK ILKLTADAKF 60
ESGDVKATVA VLSFILSSAA KHSVDSDSLS SELQQLGLPK EHATSLCRCY EEKQSPLQEH 120
LRACSLRVNR LASVGWRVDY TLSSSLLHSV EEPMVHLQLQ VVPAPGTQAQ PVSMSLSADK 180
FQVLLAELKQ AQTMMTALG 199 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara. 
Interpro
 IPR017920; COMM.
 IPR009886; HCaRG. 
Pfam
 PF07258; HCaRG 
SMART
  
PROSITE
 PS51269; COMM 
PRINTS