CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024329
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein DDI1 homolog 2 
Protein Synonyms/Alias
  
Gene Name
 Ddi2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
67SLASYGLKDGDVVILubiquitination[1]
77DVVILRQKENADPRPubiquitination[1]
153PHELSLLKERNPPLAubiquitination[1]
170LLSGDLEKFSRVLVEubiquitination[1, 2]
205FDLEAQAKIEEDIRQubiquitination[1]
283RRWAGIAKGVGTQKIubiquitination[1]
289AKGVGTQKIIGRVHLubiquitination[1]
338QCSIDLKKNVLVIGTubiquitination[1]
389ELAEAIQKSAEDAERubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 81 Ubiquitin-like.
 MOD_RES 120 120 Phosphoserine.
 MOD_RES 121 121 Phosphoserine.
 MOD_RES 128 128 Phosphoserine.
 MOD_RES 194 194 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 399 AA 
Protein Sequence
MLLTVYCVRR DLSEVTFSLQ VDADFELHNF RALCELESGI PAAESQIVYA ERPLTDNHRS 60
LASYGLKDGD VVILRQKENA DPRPAVQFSN LPRIDFSSIA VPGTSNPQQR QLPRTQAQHS 120
SPGEMASSPQ GLDNPALLRD MLLANPHELS LLKERNPPLA EALLSGDLEK FSRVLVEQQQ 180
DRARREQERI RLFSADPFDL EAQAKIEEDI RQQNIEENMT IAMEEAPESF GQVAMLYINC 240
RVNGHPVKAF VDSGAQMTIM SQACAERCNI MRLVDRRWAG IAKGVGTQKI IGRVHLAQVQ 300
IEGDFLACSF SILEEQPMDM LLGLDMLKRH QCSIDLKKNV LVIGTTGSQT TFLPEGELPE 360
CARLAYGTGR EDIRPEEIAD QELAEAIQKS AEDAERQKP 399 
Gene Ontology
 GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR021109; Peptidase_aspartic.
 IPR019103; Peptidase_aspartic_DDI1-type.
 IPR000626; Ubiquitin.
 IPR019955; Ubiquitin_supergroup. 
Pfam
 PF09668; Asp_protease
 PF00240; ubiquitin 
SMART
  
PROSITE
 PS50053; UBIQUITIN_2 
PRINTS