UniProt Accession

 B1ALD0_HUMAN; B1ALD0 

Genbank Protein ID

 AL137856 

Genbank Nucleotide ID

  

Protein Name

 AP-4 complex subunit beta-1 

Protein Synonyms/Alias

  

Gene Name

 AP4B1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
41	QRVIRMSKLDQWGQA	ubiquitination	[1]
110	TDVLVRVKGPLLAAC	ubiquitination	[2]
297	EDFVENVKSETFPAV	ubiquitination	[1]
362	LVGIDEVKRILCSPK	ubiquitination	[1, 2, 3]
369	KRILCSPKSDPTLGL	ubiquitination	[3]
401	TLVPVYGKAHWATIS	ubiquitination	[3]
409	AHWATISKCQGAERC	ubiquitination	[2, 3]
438	PLIPEENKERVQELP	ubiquitination	[1, 2, 3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 571 AA 

Protein Sequence

Gene Ontology

 GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 

Interpro

 IPR026739; AP_beta.
 IPR016342; AP_complex_bsu_1_2_4.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR015151; B-adaptin_app_sub_C.
 IPR012295; Beta2_adaptin/TBP_C_dom.
 IPR002553; Clathrin/coatomer_adapt-like_N. 

Pfam

 PF01602; Adaptin_N
 PF09066; B2-adapt-app_C 

SMART

 SM01020; B2-adapt-app_C 

PROSITE

  

PRINTS