CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028399
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein-glutamine gamma-glutamyltransferase 2 
Protein Synonyms/Alias
  
Gene Name
 TGM2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
205DVNPKFLKNAGRDCSacetylation[1]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 281 AA 
Protein Sequence
MAEELVLERC DLELETNGRD HHTADLCREK LVVRRGQPFW LTLHFEGRNY EASVDSLTFS 60
VVTGPAPSQE AGTKARFPLR DAVEEGDWTA TVVDQQDCTL SLQLTTPANA PIGLYRLSLE 120
ASTGYQGSSF VLGHFILLFN AWCPADAVYL DSEEERQEYV LTQQGFIYQG SAKFIKNIPW 180
NFGQFEDGIL DICLILLDVN PKFLKNAGRD CSRRSSPVYV GRVVSGMVNC NDDQGVLLGR 240
WDNNYGDGVS PMSWIGSVDI LRRWKNHGCQ RVKYGQCWVF A 281 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:Compara.
 GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:Compara.
 GO:0001974; P:blood vessel remodeling; IEA:Compara.
 GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Compara.
 GO:0051482; P:elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Compara.
 GO:0006917; P:induction of apoptosis; IEA:Compara.
 GO:0018153; P:isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; IEA:Compara.
 GO:0045785; P:positive regulation of cell adhesion; IEA:Compara.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara.
 GO:0050729; P:positive regulation of inflammatory response; IEA:Compara.
 GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Compara.
 GO:0051260; P:protein homooligomerization; IEA:Compara.
 GO:0060662; P:salivary gland cavitation; IEA:Compara. 
Interpro
 IPR023608; Gln_gamma-glutamylTfrase_euk.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002931; Transglutaminase-like.
 IPR001102; Transglutaminase_N. 
Pfam
 PF00868; Transglut_N 
SMART
  
PROSITE
  
PRINTS