CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042733
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 RNA polymerase-associated protein CTR9 homolog 
Protein Synonyms/Alias
  
Gene Name
 CTR9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
49GKTEEFVKLLEAARIubiquitination[1, 2, 3, 4]
164ACISFNKKDYRGALAubiquitination[4]
175GALAYYKKALRTNPGubiquitination[4]
197GMGHCFVKLNKLEKAubiquitination[4, 5]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 300 AA 
Protein Sequence
DEVIELDFDQ LPEGDEVISI LKQEHTQLHI WIALALEYYK QGKTEEFVKL LEAARIDGNL 60
DYRDHEKDQM TCLDTLAAYY VQQARKEKNK DNKKDLITQA TLLYTMADKI IMYDQNHLLG 120
RACFCLLEGD KMDQADAQFH FVLNQSPNNI PALLGKACIS FNKKDYRGAL AYYKKALRTN 180
PGCPAEVRLG MGHCFVKLNK LEKARLAFSR ALELNSKCVG ALVGLAVLEL NNKEDYSKVQ 240
HLALHAFHNT EVEAMQAESC YQLARSFHVQ EDYDQAFQYY YQATQFASSS FVLPFFGLGQ 300 
Gene Ontology
  
Interpro
 IPR001440; TPR-1.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00515; TPR_1 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS