UniProt Accession

 NANP_MOUSE; Q9CPT3 

Genbank Protein ID

 AK005566; AK021344; BC018527; BC083086 

Genbank Nucleotide ID

 BAB24126.1; BAB32381.1; AAH18527.1; AAH83086.1 

Protein Name

 N-acylneuraminate-9-phosphatase 

Protein Synonyms/Alias

 Haloacid dehalogenase-like hydrolase domain-containing protein 4; Neu5Ac-9-Pase 

Gene Name

 Nanp 

Gene Synonyms/Alias

 Hdhd4 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
51	EAEIICDKVQVKLSK	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

 REGION 12 14 Substrate binding.
 REGION 131 132 Substrate binding.
 BINDING 164 164 Substrate.  

Keyword

 3D-structure; Carbohydrate metabolism; Complete proteome; Hydrolase; Magnesium; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 248 AA 

Protein Sequence

Gene Ontology

 GO:0050124; F:N-acylneuraminate-9-phosphatase activity; ISS:UniProtKB.
 GO:0008967; F:phosphoglycolate phosphatase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
 GO:0006045; P:N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0046380; P:N-acetylneuraminate biosynthetic process; ISS:UniProtKB. 

Interpro

 IPR023214; HAD-like_dom.
 IPR011950; HAD-SF_hydro_IA_CTE7.
 IPR006439; HAD-SF_hydro_IA_v1.
 IPR005833; Haloacid_DH/epoxide_hydro. 

Pfam

 PF13419; HAD_2 

SMART

  

PROSITE

  

PRINTS

 PR00413; HADHALOGNASE.