CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037226
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tubulin polyglutamylase TTLL4 
Protein Synonyms/Alias
  
Gene Name
 TTLL4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
332SDSQDPTKEIRFTEAubiquitination[1]
350LTARGFEKMPRQGCQubiquitination[1]
917VTAQKMKKAYYLTQKubiquitination[1]
998KYHGNKLKGVDLLRSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1135 AA 
Protein Sequence
MASAGTQHYS IGLRQKNSFK QSGPSGTVPA TPPEKPSEGR VWPQAHQQVK PIWKLEKKQV 60
ETLSAGLGPG LLGVPPQPAY FFCPSTLCSS GTTAVIAGHS SSCYLHSLPD LFNSTLLYRR 120
SSYRQKPYQQ LESFCLRSSP SEKSPFSLPQ KSLPVSLTAN KATSSMVFSM AQPMASSSTE 180
PYLCLAAAGE NPSGKSLASA ISGKIPSPLS SSYKPMLNNN SFMWPNSTPV PLLQTTQGLK 240
PVSPPKIQPV SWHHSGGTGD CAPQPVDHKV PKSIGTVPAD ASAHIALSTA SSHDTSTTSV 300
ASSWYNRNNL AMRAEPLSCA LDDSSDSQDP TKEIRFTEAV RKLTARGFEK MPRQGCQLEQ 360
SSFLNPSFQW NVLNRSRRWK PPAVNQQFPQ EDAGSVRRVL PGASDTLGLD NTVFCTKRIS 420
IHLLASHASG LNHNPACESV IDSSAFGEGK APGPPFPQTL GIANVATRLS SIQLGQSEKE 480
RPEEARELDS SDRDISSATD LQPDQAETED TEEELVDGLE DCCSRDENEE EEGDSECSSL 540
SAVSPSESVA MISRSCMEIL TKPLSNHEKV VRPALIYSLF PNVPPTIYFG TRDERVEKLP 600
WEQRKLLRWK MSTVTPNIVK QTIGRSHFKI SKRNDDWLGC WGHHMKSPSF RSIREHQKPA 660
SARGIGIQVI HKWSQLPKRR PLLVQRYLHK PYLISGSKFD LRIYVYVTSY DPLRIYLFSD 720
GLVRFASCKY SPSMKSLGNK FMHLTNYSVN KKNAEYQANA DEMACQGHKW ALKALWNYLS 780
QKGVNSDAIW EKIKDVVVKT IISSEPYVTS LLKMYVRRPY SCHELFGFDI MLDENLKPWV 840
LEVNISPSLH SSSPLDISIK GQMIRDLLNL AGFVLPNAED IISSPSSCSS STTSLPTSPG 900
DKCRMAPEHV TAQKMKKAYY LTQKIPDQDF YASVLDVLTP DDVRILVEME DEFSRRGQFE 960
RIFPSHISSR YLRFFEQPRY FNILTTQWEQ KYHGNKLKGV DLLRSWCYKG FHMGVVSDSA 1020
PVWSLPTSLL TISKDDVILN AFSKSETSKL GKQSSCEVSL LLSEDGTTPK SKKTQAGLSP 1080
YPQKPSSSKD SEDTSKEPSL STQTLPVIKC SGQTSRLSAS STFQSISDSL LAVSP 1135 
Gene Ontology
 GO:0004835; F:tubulin-tyrosine ligase activity; IEA:InterPro.
 GO:0006464; P:cellular protein modification process; IEA:InterPro. 
Interpro
 IPR004344; Tub_tyr_ligase. 
Pfam
 PF03133; TTL 
SMART
  
PROSITE
 PS51221; TTL 
PRINTS