CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035644
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome P450, family 2, subfamily s, polypeptide 1 
Protein Synonyms/Alias
 Protein Cyp2s1 
Gene Name
 Cyp2s1 
Gene Synonyms/Alias
 rCG_53865 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
128ERWKQLRKFTLLALRacetylation[1]
436FLPYSLGKRVCLGEGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 499 AA 
Protein Sequence
MEAASTWALL LALLLLLLAL TLPRTPARGQ LPPGPTPLPL LGNLLQLRPG ALYSGFLRLS 60
KKYGPVFTVH LGPWRRVVVL VGHDAIREAL GGQAEEFSGR GTLATLDKTF DGHGVFFANG 120
ERWKQLRKFT LLALRDLGMG KREGEELIQE EVQNLVKAFQ RTEGRPFNPS MLLAQATSNV 180
VCSLIFGIRL PYEDKEFQAV IQAASGTLLG ISSPWGQAYE MFSWLLQPLP GPHTQLQHHL 240
GTLAAFTIQQ VQRHQGRSHT SGPARDVVDA FLQKMAQEKE DPGTEFTEKN LLMTVTYLLF 300
AGTMTIGATI RYALLLLLKY PQVQKRVREE LIQELGPSRT PSLSDRVRLP YTDAVLHEAQ 360
RLLALVPMGM PHTVTKTTSF RGYTLPKGTE VFPLIGSVLH DPAVFRNPEE FHPSRFLDDD 420
GRIRKHEAFL PYSLGKRVCL GEGLARAELW LFFTSILQAF SLDTPCPPGD LSLKPAVRGL 480
FNIPPDFQLQ VWPTGDQSR 499 
Gene Ontology
 GO:0043231; C:intracellular membrane-bounded organelle; IDA:RGD.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR002401; Cyt_P450_E_grp-I.
 IPR008067; Cyt_P450_E_grp-I_CYP2A-like. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
  
PRINTS
 PR00463; EP450I.
 PR01684; EP450ICYP2A.
 PR00385; P450.