CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025779
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA4032 protein 
Protein Synonyms/Alias
  
Gene Name
 Mfn1 
Gene Synonyms/Alias
 mKIAA4032 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
141MTEGSDEKKSVKTVNubiquitination[1]
237KVNERLSKPNIFILNubiquitination[1]
403NLLTLDVKKKIKEVTubiquitination[1]
407LDVKKKIKEVTEEVAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 749 AA 
Protein Sequence
GKALSRCIMA ETVSPLKHFV LAKKAITAIF GQLLEFVTEG SHFVEATYRN PELDRIASED 60
DLVEIQGYRN KLAVIGEVLS RRHMKVAFFG RTSSGKSSVI NAMLWDKVLP SGIGHTTNCF 120
LSVEGTDGDK AYLMTEGSDE KKSVKTVNQL AHALHMDKDL KAGCLVHVFW PKAKCALLRD 180
DLVLVDSPGT DVTTELDIWI DKFCLDADVF VLVANSESTL MNTEKHFFHK VNERLSKPNI 240
FILNNRWDAS ASEPEYMEDV RRQHMERCLH FLVEELKVVS PSEARNRIFF VSAKEVLNSR 300
KHKAQGMPEG GGALAEGFQA RLQEFQNFEQ TFEECISQSA VKTKFEQHTI RAKQILDTVK 360
NILDSVNVAA AEKRVYSMEE REDQIDRLDF IRNQMNLLTL DVKKKIKEVT EEVANKVSCA 420
MTDEICRLSV LVDEFCSEFH PTPSVLKVYK SELNKHIEDG MGRNLADRCT NEVNASILQS 480
QQEIIENLKP LLPAGIQNKL HTLIPCKKFD LSYDLNCHKL CSDFQEDIVF RFSLGWSSLV 540
HRFLGSTNAQ RVLLGLSEPI FQVPRSLAST PTAPSNPAAP DNAAQEELMI TLITGLASLT 600
SRTSMGIIVV GGVIWKTVGW KLISVTLSMY GALYLYERLT WTTRAKERAF KQQFVNYATE 660
KLQMIVSFTS ANCSHQVQQE MATTFARLCQ QVDVTQKHLE EEIARLSKEI DQLEKIQNNS 720
KLLRNKAIQL ESELENFSKQ FLHPSSGES 749 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005741; C:mitochondrial outer membrane; IEA:InterPro.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0008053; P:mitochondrial fusion; IMP:MGI. 
Interpro
 IPR001401; Dynamin_GTPase.
 IPR006884; Fzo/mitofusin_HR2.
 IPR027088; Mitofusin-1.
 IPR027094; Mitofusin_fam.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00350; Dynamin_N
 PF04799; Fzo_mitofusin 
SMART
  
PROSITE
  
PRINTS