UniProt Accession

 VP26B_MOUSE; Q8C0E2; Q3TN45; Q8K2V3 

Genbank Protein ID

 AK031589; AK150929; AK155578; AK165539; AK171154; BC029758; BC049180; BC052721; BC062972 

Genbank Nucleotide ID

 BAC27465.1; BAE29967.1; BAE33333.1; BAE38244.1; BAE42279.1; AAH29758.1; AAH49180.1; AAH52721.1; AAH62972.1 

Protein Name

 Vacuolar protein sorting-associated protein 26B 

Protein Synonyms/Alias

 Vesicle protein sorting 26B 

Gene Name

 Vps26b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
55	GKVSLSLKNPNKRLE	ubiquitination	[1]
286	EEERRYFKQQEVVLW	acetylation	[2]
301	RKGDIVRKSMSHQAA	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. 

Sequence Annotation

 MOD_RES 302 302 Phosphoserine.
 MOD_RES 304 304 Phosphoserine.
 MOD_RES 319 319 Phosphoserine (By similarity).  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 336 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0030904; C:retromer complex; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007034; P:vacuolar transport; IEA:InterPro. 

Interpro

 IPR005377; VPS26. 

Pfam

 PF03643; Vps26 

SMART

  

PROSITE

  

PRINTS