CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024683
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable Xaa-Pro aminopeptidase 3 
Protein Synonyms/Alias
 X-Pro aminopeptidase 3; Aminopeptidase P3; APP3 
Gene Name
 Xpnpep3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
148GKQLPSHKAMLFVPRacetylation[1]
194EFQHLLPKLRAETNMacetylation[1]
253IKSPAEIKRMQIAGKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 METAL 331 331 Manganese 2 (By similarity).
 METAL 342 342 Manganese 1 (By similarity).
 METAL 342 342 Manganese 2 (By similarity).
 METAL 423 423 Manganese 1 (By similarity).
 METAL 450 450 Manganese 1 (By similarity).
 METAL 474 474 Manganese 1 (By similarity).
 METAL 474 474 Manganese 2 (By similarity).  
Keyword
 Complete proteome; Hydrolase; Manganese; Metal-binding; Mitochondrion; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
MLSLLSTPRL VPVIARLRGL SGCMSCLQRR YSLQPVPVKE IPNRYLGQPS PVTHPHLLRP 60
GEVTPGLSQV EYALRRHKLM ALVHKEAQGH SGTDHTVVVL SNPIHYMSND IPYTFHQDNS 120
FLYLCGFQEP DSILVLQSCS GKQLPSHKAM LFVPRRDPGR ELWDGPRSGT DGAIALTGVD 180
DAYPLEEFQH LLPKLRAETN MVWYDWMKPS HAQLHSDYMQ PLTEAKATSK NKVRSVQHLI 240
QHLRLIKSPA EIKRMQIAGK LTSEAFIETM FASKAPVDEA FLYAKFEFEC RARGADILAY 300
PPVVAGGNRS NTLHYVKNNQ LIKDGEMVLL DGGCESSCYV SDITRTWPVN GRFTAPQAEL 360
YEAVLEIQKA CLTLCSPGTS LENIYSMMLT LMGQKLKDLG IIKTSKESAF KAARKYCPHH 420
VGHYLGMDVH DTPDMPRSLP LQPGMVITVE PGIYIPEGDT DAPEKFRGLG VRIEDDVVVT 480
QDSPLILSAD CPKEVNDIEQ ICSRTS 506 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0004177; F:aminopeptidase activity; IEA:InterPro.
 GO:0030145; F:manganese ion binding; IEA:InterPro.
 GO:0009987; P:cellular process; IEA:InterPro. 
Interpro
 IPR007865; Aminopep_P_N.
 IPR000994; Pept_M24_structural-domain. 
Pfam
 PF05195; AMP_N
 PF00557; Peptidase_M24 
SMART
 SM01011; AMP_N 
PROSITE
  
PRINTS