| Tag | Content |
|---|
| CPLM ID | CPLM-004462 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 823 |
Protein Synonyms/Alias | Zinc finger protein ZFP-36 |
Gene Name | ZNF823 |
Gene Synonyms/Alias | ZFP36 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 60 | GDQCQNAKRNLRSHT | ubiquitination | [1] | | 581 | EKTHTGEKLYECKEC | ubiquitination | [1] | | 586 | GEKLYECKECGKALS | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 4 97 KRAB.
ZN_FING 164 186 C2H2-type 1.
ZN_FING 192 214 C2H2-type 2.
ZN_FING 220 242 C2H2-type 3.
ZN_FING 248 270 C2H2-type 4.
ZN_FING 276 298 C2H2-type 5.
ZN_FING 304 326 C2H2-type 6.
ZN_FING 332 354 C2H2-type 7.
ZN_FING 360 382 C2H2-type 8.
ZN_FING 388 410 C2H2-type 9.
ZN_FING 416 438 C2H2-type 10.
ZN_FING 444 465 C2H2-type 11; atypical.
ZN_FING 471 493 C2H2-type 12.
ZN_FING 499 521 C2H2-type 13.
ZN_FING 527 549 C2H2-type 14.
ZN_FING 555 577 C2H2-type 15.
ZN_FING 583 605 C2H2-type 16. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 610 AA |
Protein Sequence | MDSVAFEDVA VNFTQEEWAL LGPSQKSLYR NVMQETIRNL DCIEMKWEDQ NIGDQCQNAK 60
RNLRSHTCEI KDDSQCGETF GQIPDSIVNK NTPRVNPCDS GECGEVVLGH SSLNCNIRVD 120
TGHKSCEHQE YGEKPYTHKQ RGKAISHQHS FQTHERPPTG KKPFDCKECA KTFSSLGNLR 180
RHMAAHHGDG PYKCKLCGKA FVWPSLFHLH ERTHTGEKPY ECKQCSKAFP FYSSYLRHER 240
IHTGEKAYEC KQCSKAFPDY STYLRHERTH TGEKPYKCTQ CGKAFSCYYY TRLHERTHTG 300
EQPYACKQCG KTFYHHTSFR RHMIRHTGDG PHKCKICGKG FDCPSSVRNH ETTHTGEKPY 360
ECKQCGKVLS HSSSFRSHMI THTGDGPQKC KICGKAFGCP SLFQRHERTH TGEKPYQCKQ 420
CGKAFSLAGS LRRHEATHTG VKPYKCQCGK AFSDLSSFQN HETTHTGEKP YECKECGKAF 480
SCFKYLSQHK RTHTVEKPYE CKTCRKAFSH FSNLKVHERI HSGEKPYECK ECGKAFSWLT 540
CLLRHERIHT GEKPYECLQC GKAFTRSRFL RGHEKTHTGE KLYECKECGK ALSSLRSLHR 600
HKRTHWKDTL 610 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |