| Tag | Content |
|---|
| CPLM ID | CPLM-008905 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable ATP-dependent RNA helicase DDX6 |
Protein Synonyms/Alias | ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK homolog |
Gene Name | Ddx6 |
Gene Synonyms/Alias | Hlr2; Rck |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 104 | EFEDYCLKRELLMGI | acetylation | [1] | | 353 | RVELLAKKISQLGYS | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | In the process of mRNA degradation, may play a role in mRNA decapping. |
Sequence Annotation | DOMAIN 127 298 Helicase ATP-binding.
DOMAIN 308 468 Helicase C-terminal.
NP_BIND 140 147 ATP (By similarity).
MOTIF 96 124 Q motif.
MOTIF 246 249 DEAD box.
MOD_RES 36 36 Phosphothreonine (By similarity). |
Keyword | ATP-binding; Complete proteome; Cytoplasm; Helicase; Hydrolase; Nucleotide-binding; Phosphoprotein; Reference proteome; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 483 AA |
Protein Sequence | MSTARTENPV IMGLSSQNGQ LRGPVKASAG PGGGGTQPQP QLNQLKNTST INNGTPQQAQ 60
SMAATIKPGD DWKKTLKLPP KDLRIKTSDV TSTKGNEFED YCLKRELLMG IFEMGWEKPS 120
PIQEESIPIA LSGRDILARA KNGTGKSGAY LIPLLERLDL KKDNIQAMVI VPTRELALQV 180
SQICIQVSKH MGGAKVMATT GGTNLRDDIM RLDDTVHVVI ATPGRILDLI KKGVAKVDHV 240
QMIVLDEADK LLSQDFVQIM EDIILTLPKN RQILLYSATF PLSVQKFMNS HLQKPYEINL 300
MEELTLKGVT QYYAYVTERQ KVHCLNTLFS RLQINQSIIF CNSSQRVELL AKKISQLGYS 360
CFYIHAKMRQ EHRNRVFHDF RNGLCRNLVC TDLFTRGIDI QAVNVVINFD FPKLAETYLH 420
RIGRSGRFGH LGLAINLITY DDRFNLKSIE EQLGTEIKPI PSNIDKSLYV AEYHSEPAED 480
EKP 483 |
Gene Ontology | GO:0000932; C:cytoplasmic mRNA processing body; ISO:MGI. GO:0010494; C:cytoplasmic stress granule; IEA:Compara. GO:0016442; C:RNA-induced silencing complex; IEA:Compara. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0033962; P:cytoplasmic mRNA processing body assembly; ISO:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |