| Tag | Content |
|---|
| CPLM ID | CPLM-010675 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Urea transporter 1 |
Protein Synonyms/Alias | Solute carrier family 14 member 1; Urea transporter B; UT-B; Urea transporter, erythrocyte |
Gene Name | Slc14a1 |
Gene Synonyms/Alias | UT11; UT3 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 361 | IYRMPLSKVTYSEEN | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Low-affinity facilitative urea transporter that allow rapid equilibration between the urinary space and the hyperosmotic interstitium. the rate of urea conduction is increased by hypoosmotic stress. Mediates urea transport in erythrocytes (By similarity). |
Sequence Annotation | CARBOHYD 206 206 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 384 AA |
Protein Sequence | MEDIPTMVKV DRGESQILSC RGRRCGLKVL GYVTGDMKEF ANWLKDKPVV LQFMDWILRG 60
ISQVVFVSNP ISGILILAGL LVQNPWWALC GCVGTVVSTL TALLLSQDRS AIAAGLQGYN 120
ATLVGILMAV FSDKGDYFWW LIFPVSAMSM TCPVFSSALS SLFSKWDLPV FTLPFNMALS 180
LYLSATGHYN TFFPSKLFMP VSSVPNITWS ELSALELLKS LPVGVGQIYG CDNPWTGAIF 240
LCAILLSSPL MCLHAAIGSL LGVIAGLSLA APFKDIYSGL WGFNSSLACI AIGGMFMALT 300
WQTHLLALAC ALFTAYFGAC MTHLMAAVHL PACTWSFCLA TLLFLLLTTE NPNIYRMPLS 360
KVTYSEENRI FYLQNKKRVV DSPL 384 |
Gene Ontology | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015204; F:urea transmembrane transporter activity; IDA:RGD. GO:0005372; F:water transmembrane transporter activity; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |