CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040411
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Annexin 
Protein Synonyms/Alias
  
Gene Name
 Anxa4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
189SFKRLYGKSLYSFIKacetylation[1]
196KSLYSFIKGDTSGDYacetylation[1]
196KSLYSFIKGDTSGDYubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Annexin; Calcium; Calcium/phospholipid-binding; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 215 AA 
Protein Sequence
AASGFNATED AQTLRKAMKG LGTDEDAIIG ILAYRNTAQR QEIRSAYKST IGRAGRDEGN 60
YLDDALMKQD AQELYEAGEK RWGTDEVKFL SILCSRNRNH LLHVFDEYKR ISQKDIEQSI 120
KSETSGSFED ALLAIVKCMR SKPSYFAERL YKSMKGLGTD DNTLIRVMVS RAEIDMLDIR 180
ASFKRLYGKS LYSFIKGDTS GDYRKVLLVL CGGDD 215 
Gene Ontology
 GO:0016324; C:apical plasma membrane; ISA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
 GO:0001822; P:kidney development; ISA:MGI. 
Interpro
 IPR001464; Annexin.
 IPR018502; Annexin_repeat.
 IPR018252; Annexin_repeat_CS.
 IPR002391; AnnexinIV. 
Pfam
 PF00191; Annexin 
SMART
 SM00335; ANX 
PROSITE
 PS00223; ANNEXIN 
PRINTS
 PR00196; ANNEXIN.