CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039508
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Corticosteroid 11-beta-dehydrogenase isozyme 1 
Protein Synonyms/Alias
  
Gene Name
 Hsd11b1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
56VIVTGASKGIGREMAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 224 AA 
Protein Sequence
MATGRPEPGP CLMAVMKNYL LPILVLFLAY YYYSTNEEFR PEMLQGKKVI VTGASKGIGR 60
EMAYHLSKMG AHVVLTARSE EGLQKVVSRC LELGAASAHY IAGTMEDMTF AEQFIVKAGK 120
LMGGLDMLIL NHITQTSLSL FHDDIHSVRR VMEVNFLSYV VMSTAALPML KQSNGSIAVI 180
SSLAGKMTQP MIAPYSASKF ALDGFFSTIR TELYITKVNV SITL 224 
Gene Ontology
 GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; IDA:MGI.
 GO:0030324; P:lung development; IMP:MGI. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.