CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017540
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein boule-like 
Protein Synonyms/Alias
  
Gene Name
 BOLL 
Gene Synonyms/Alias
 BOULE 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
73NDRAGVSKGYGFVTFacetylation[1]
99EAEKLNYKDKKLNIGacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
 Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation (By similarity). 
Sequence Annotation
 DOMAIN 33 110 RRM.
 DOMAIN 164 194 DAZ-like.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Developmental protein; Differentiation; Reference proteome; RNA-binding; Spermatogenesis; Translation regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 283 AA 
Protein Sequence
MQTDSLSPSP NPVSPVPLNN PTSAPRYGTV IPNRIFVGGI DFKTNESDLR KFFSQYGSVK 60
EVKIVNDRAG VSKGYGFVTF ETQEDAQKIL QEAEKLNYKD KKLNIGPAIR KQQVGIPRSS 120
IMPAAGTMYL TTSTGYPYTY HNGVAYFHTP EVTSVPPPWP SRSVCSSPVM VAQPIYQQPA 180
YHYQATTQYL PGQWQWSVPQ PSASSAPFLY LQPSEVIYQP VEIAQDGGCV PPPLSLMETS 240
VPEPYSDHGV QATYHQVYAP SAITMPAPVM QPEPIKTVWS IHY 283 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0008494; F:translation activator activity; IDA:UniProtKB.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007126; P:meiosis; IDA:MGI.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0045948; P:positive regulation of translational initiation; IDA:UniProtKB.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS