UniProt Accession

 E9PCN5_HUMAN; E9PCN5 

Genbank Protein ID

 AC138972; AC139452 

Genbank Nucleotide ID

  

Protein Name

 CCR4-NOT transcription complex subunit 10 

Protein Synonyms/Alias

  

Gene Name

 CNOT10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
150	NKDGSNHKAESGALI	ubiquitination	[1, 2, 3]
176	VRAYIQMKSLKACKR	ubiquitination	[3]
536	EQDQGSDKGENEAME	ubiquitination	[2]
547	EAMESSGKRAPQCYP	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Repeat; TPR repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 609 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR001440; TPR-1.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 

Pfam

 PF00515; TPR_1 

SMART

 SM00028; TPR 

PROSITE

 PS50005; TPR 

PRINTS