UniProt Accession

 PYRI_ECOLI; P0A7F3; P00478; Q2M663 

Genbank Protein ID

 K01472; U14003; U00096; AP009048; M28578 

Genbank Nucleotide ID

 AAA24477.1; AAA97141.1; AAC77201.1; BAE78243.1; AAA24487.1 

Protein Name

 Aspartate carbamoyltransferase regulatory chain 

Protein Synonyms/Alias

  

Gene Name

 pyrI 

Gene Synonyms/Alias

 b4244; JW4203 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
6	**MTHDNKLQVEAIK	acetylation	[1]
13	KLQVEAIKRGTVIDH	acetylation	[1]
28	IPAQIGFKLLSLFKL	acetylation	[1]
34	FKLLSLFKLTETDQR	acetylation	[1]
94	DNYEVVGKSRPSLPE	acetylation	[1]
137	RANDIALKCKYCEKE	acetylation	[1]
143	LKCKYCEKEFSHNVV	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Involved in allosteric regulation of aspartate carbamoyltransferase. 

Sequence Annotation

 METAL 109 109 Zinc.
 METAL 114 114 Zinc.
 METAL 138 138 Zinc.
 METAL 141 141 Zinc.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Metal-binding; Pyrimidine biosynthesis; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 153 AA 

Protein Sequence

Gene Ontology

 GO:0009347; C:aspartate carbamoyltransferase complex; IEA:InterPro.
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0008270; F:zinc ion binding; IDA:EcoCyc.
 GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
 GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:HAMAP. 

Interpro

 IPR020545; Asp_carbamoyltransf_reg_N.
 IPR002801; Asp_carbamoylTrfase_reg.
 IPR020542; Asp_carbamoyltrfase_reg_C. 

Pfam

 PF01948; PyrI
 PF02748; PyrI_C 

SMART

  

PROSITE

  

PRINTS