CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015844
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Fibronectin type III and SPRY domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Fsd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
10DQREALRKIITTLAMubiquitination[1]
214FEGPPRLKEDHPWMVubiquitination[1]
367VRFEPDSKAFGLGVAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May be involved in microtubule organization and stabilization (By similarity). 
Sequence Annotation
 DOMAIN 105 162 COS.
 DOMAIN 165 267 Fibronectin type-III.
 DOMAIN 290 477 B30.2/SPRY.  
Keyword
 Alternative splicing; Cell cycle; Cell division; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Mitosis; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 496 AA 
Protein Sequence
MEDQREALRK IITTLAMKNE ETQTFIYSLK QMLLNVEANS AKVQEDLEAE FQSLTSVLEE 60
LKESMLMKIK QDRASRTYEL QNQLAACTRA LESSEELLET ANQTLQASDS EDFSQAAKEI 120
KDGITMAPAF RLSLKAKVSD NMSHLMVDFA QERQMLQALK FLPVPSAPTI DLAESLVSDN 180
CVTLVWHMPD EDSKIDHYVL EYRKTNFEGP PRLKEDHPWM VVEGIRQTEH TLTGLKFDMK 240
YMNIRVKACN KAVAGEFSEP VTLETPAFMF RLDGSTSHQN LRVEDLSAEW DAMGGKVQDI 300
KAREKEGKGR TASPVNSPAR GTPSPKRMSS GRGGRDRFTA ESYTVLGDTL IDGGEHYWEV 360
RFEPDSKAFG LGVAYRSLGR FEQLGKTAAS WCLHANNWLQ ASFTAKHANK VKVLDSPVPD 420
CLGVHCDFHQ GLLSFYNART KQLLHTFKAK FTQPLLPAFT VWCGSFQVTT GLQVPSAVRC 480
LQKRGSATSS SNTSLT 496 
Gene Ontology
 GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR003649; Bbox_C.
 IPR008985; ConA-like_lec_gl_sf.
 IPR017903; COS_domain.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR003877; SPRY_rcpt. 
Pfam
 PF00041; fn3
 PF00622; SPRY 
SMART
 SM00502; BBC
 SM00060; FN3 
PROSITE
 PS50188; B302_SPRY
 PS51262; COS
 PS50853; FN3 
PRINTS