| Tag | Content |
|---|
| CPLM ID | CPLM-016395 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ELMO domain-containing protein 2 |
Protein Synonyms/Alias | |
Gene Name | Elmod2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 150 | KLTARISKQWADIGF | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. |
Sequence Annotation | DOMAIN 126 282 ELMO. |
Keyword | Complete proteome; GTPase activation; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 293 AA |
Protein Sequence | MFVSLWEFFY GHFFRFWMKW LLRQMTGKCE LQRIFDTYGG AQRTYRIENS LTYSKNKVLQ 60
NATRVAQSEL DRCIANIMKE KNICSEKDTS FQICMRTCLL QITGYKQLYH DVENVRKKPY 120
DSANAQHEKM LLKLWSLLMP TKKLTARISK QWADIGFQGD DPKTDFRGMG ILGLINLVYF 180
SENYTSEAHQ ILSRSNHPKL GYSYAIVGIN LTEMAYSLLK SEALKLHLYN FVPGVPTMEH 240
FHQFYCYLVY EFDKFWLEEE PESIMYFNLY REKFHERIKG LLMDCNAVLT LKT 293 |
Gene Ontology | GO:0005856; C:cytoskeleton; IEA:InterPro. GO:0005096; F:GTPase activator activity; ISS:UniProtKB. GO:0006909; P:phagocytosis; IEA:InterPro. GO:0050688; P:regulation of defense response to virus; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |