CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040475
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nuclear receptor subfamily 2 group F member 6 
Protein Synonyms/Alias
  
Gene Name
 Nr2f6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
233AFQEQVDKLGRLQVDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 254 AA 
Protein Sequence
XGQVQWKALR RVHLRGLQEF LQAQHPPQSQ LHLPGFAGTS VGTLACVSRS NRDCQIDQHH 60
RNQCQYCRLK KCFRVGMRKE AVQRGRIPHA LPGPAACSPP GATGVEPFTG PPVSELIAQL 120
LRAEPYPAAG RFGGGGAVLG IDNVCELAAR LLFSTVEWAR HAPFFPELPA ADQVALLRLS 180
WSELFVLNAA QAALPLHTAP LLAAAGLHAA PMAAERAVAF MDQVRAFQEQ VDKLGRLQVD 240
AAEYGCLKAI ALFT 254 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IMP:MGI.
 GO:0043153; P:entrainment of circadian clock by photoperiod; IMP:MGI.
 GO:0030522; P:intracellular receptor signaling pathway; IEA:GOC.
 GO:0048666; P:neuron development; IMP:MGI. 
Interpro
 IPR003068; COUP_TF.
 IPR008946; Nucl_hormone_rcpt_ligand-bd.
 IPR000536; Nucl_hrmn_rcpt_lig-bd_core.
 IPR001723; Str_hrmn_rcpt.
 IPR001628; Znf_hrmn_rcpt.
 IPR013088; Znf_NHR/GATA. 
Pfam
 PF00104; Hormone_recep
 PF00105; zf-C4 
SMART
 SM00430; HOLI
 SM00399; ZnF_C4 
PROSITE
 PS51030; NUCLEAR_REC_DBD_2 
PRINTS
 PR01282; COUPTNFACTOR.
 PR00398; STRDHORMONER.