CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013151
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 51 
Protein Synonyms/Alias
  
Gene Name
 Ccdc51 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
126GLEAQQTKLKEVRDRacetylation[1, 2, 3]
175AEDSEREKFSLFSAAacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 406 AA 
Protein Sequence
MTGCSPVFAM QHVVGVPRIL VRRTFLGTDV TMTRTLCSPG PREKRPEAAA LGLFHRLPEL 60
GRTLSHTVRH QAASTAKAWW DRYEEFVGLN EVREAQGNVT EAEKVFMVAR GLVREAREGL 120
EAQQTKLKEV RDRLDRVSRE DNQYLELATL EHRMLQEEKR LRIAYLRAED SEREKFSLFS 180
AAVRESHEKE RTRAERTKNW SLIGSVLGAL IGVAGSTYVN RVRLQELKAL LLEAQKGPAS 240
LQEAIREQAS SYSLQQKDLQ DLMMDLRGLV HAEQGQGSGS PTGSSTRGKD IDGLSATMKE 300
QLRHSRQVYS CLEGLREQLD GLEKTCSQMA GVLQLAQAPA HPGTVGPVDG ALPSSLLEHG 360
SVILALSEME QRLEAQANRN TVSSTLVTCV TFLATLPLLY MLFKTS 406 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005634; C:nucleus; IEA:Compara. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS