CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040259
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pre-B-cell leukemia transcription factor 3 
Protein Synonyms/Alias
  
Gene Name
 Pbx3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
128RYKKNIGKFQEEANLacetylation[1, 2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 196 AA 
Protein Sequence
XACNEFTTHV MNLLREQSRT RPISPKEIER MVGIIHRKFS SIQMQLKQST CEAVMILRSR 60
FLDARRKRRN FSKQATEILN EYFYSHLSNP YPSEEAKEEL AKKCSITVSQ VSNWFGNKRI 120
RYKKNIGKFQ EEANLYAAKT AVTAAHAVAA AVQNNQTNSP TTPNSGEYGL LTPYSARQAS 180
ATASQPTDSE ASALLG 196 
Gene Ontology
 GO:0005667; C:transcription factor complex; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008344; P:adult locomotory behavior; IMP:MGI.
 GO:0021516; P:dorsal spinal cord development; IMP:MGI.
 GO:0048666; P:neuron development; IMP:MGI.
 GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IMP:MGI.
 GO:0007585; P:respiratory gaseous exchange; IMP:MGI. 
Interpro
 IPR017970; Homeobox_CS.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR005542; PBX. 
Pfam
 PF00046; Homeobox
 PF03792; PBC 
SMART
 SM00389; HOX 
PROSITE
 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2 
PRINTS