| Tag | Content |
|---|
| CPLM ID | CPLM-022564 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | REST corepressor 3 |
Protein Synonyms/Alias | |
Gene Name | RCOR3 |
Gene Synonyms/Alias | KIAA1343 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 20 | EFDPGATKYTDKDNG | ubiquitination | [1] | | 325 | NKTVGQVKNFFVNYR | ubiquitination | [1] |
|
Reference | [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [ PMID: 21890473] |
Functional Description | May act as a component of a corepressor complex that represses transcription (Potential). |
Sequence Annotation | DOMAIN 1 83 ELM2.
DOMAIN 84 135 SANT 1.
DOMAIN 285 336 SANT 2.
MOD_RES 156 156 Phosphoserine. |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 495 AA |
Protein Sequence | MRVGAEYQAR IPEFDPGATK YTDKDNGGML VWSPYHSIPD AKLDEYIAIA KEKHGYNVEQ 60
ALGMLFWHKH NIEKSLADLP NFTPFPDEWT VEDKVLFEQA FSFHGKSFHR IQQMLPDKTI 120
ASLVKYYYSW KKTRSRTSLM DRQARKLANR HNQGDSDDDV EETHPMDGND SDYDPKKEAK 180
KEGNTEQPVQ TSKIGLGRRE YQSLQHRHHS QRSKCRPPKG MYLTQEDVVA VSCSPNAANT 240
ILRQLDMELI SLKRQVQNAK QVNSALKQKM EGGIEEFKPP ESNQKINARW TTEEQLLAVQ 300
GVRKYGKDFQ AIADVIGNKT VGQVKNFFVN YRRRFNLEEV LQEWEAEQGT QASNGDASTL 360
GEETKSASNV PSGKSTDEEE EAQTPQAPRT LGPSPPAPSS TPTPTAPIAT LNQPPPLLRP 420
TLPAAPALHR QPPPLQQQAR FIQPRPTLNQ PPPPLIRPAN SMPPRLNPRP VLSTVGGQQP 480
PSLIGIQTDS QSSLH 495 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003682; F:chromatin binding; IEA:InterPro. GO:0003677; F:DNA binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |