UniProt Accession

 ATOX1_RAT; Q9WUC4; Q549B3 

Genbank Protein ID

 AF177671; AF127137; BC058458 

Genbank Nucleotide ID

 AAD53914.1; AAD27844.1; AAH58458.1 

Protein Name

 Copper transport protein ATOX1 

Protein Synonyms/Alias

 ATX1 homolog protein Rah1; Metal transport protein ATX1 

Gene Name

 Atox1 

Gene Synonyms/Alias

 Rah1 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
25	AVSRVLNKLGGVEFN	acetylation	[1]
60	ATLNKTGKAVSYLGP	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity). 

Sequence Annotation

 DOMAIN 2 68 HMA.
 METAL 12 12 Copper (By similarity).
 METAL 15 15 Copper (By similarity).  

Keyword

 Chaperone; Complete proteome; Copper; Copper transport; Direct protein sequencing; Ion transport; Metal-binding; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 68 AA 

Protein Sequence

Gene Ontology

 GO:0016531; F:copper chaperone activity; IEA:Compara.
 GO:0005507; F:copper ion binding; IMP:RGD.
 GO:0006878; P:cellular copper ion homeostasis; IEA:Compara.
 GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.
 GO:0006979; P:response to oxidative stress; IDA:RGD. 

Interpro

 IPR017969; Heavy-metal-associated_CS.
 IPR006121; HeavyMe-assoc_HMA. 

Pfam

 PF00403; HMA 

SMART

  

PROSITE

 PS01047; HMA_1
 PS50846; HMA_2 

PRINTS