CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040767
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 BAP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
257PELIQTHKSQESQLPubiquitination[1]
612SGEKYSPKELLALLKubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MNKGWLELES DPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ GPVYGFIFLF KWIEERRSRR 60
KVSTLVDDTS VIDDDIVNNM FFAHQLIPNS CATHALLSVL LNCSSVDLGP TLSRMKDFTK 120
GFSPESKGYA IGNAPELAKA HNSHARPEPR HLPEKQNGLS AVRTMEAFHF VSYVPITGRL 180
FELDGLKVYP IDHGPWGEDE EWTDKARRVI MERIGLATAG IKYEARLHVL KVNRQTVLEA 240
LQQLIRVTQP ELIQTHKSQE SQLPEESKSA SNKSPLVLEA NRAPAASEGN HTDGAEEAAG 300
SCAQAPSHSP PNKPKLVVKP PGSSLNGVHP NPTPIVQRLP AFLDNHNYAK SPMQEEEDLA 360
AGVGRSRVPV RPPQQYSDDE DDYEDDEEDD VQNTNSALRY KGKGTGKPGA LSGSADGQLS 420
VLQPNTINVL AEKLKESQKD LSIPLSIKTS SGAGSPAVAV PTHSQPSPTP SNESTDTASE 480
IGSAFNSPLR SPIRSANPTR PSSPVTSHIS KVLFGEDDSL LRVDCIRYNR AVRDLGPVIS 540
TGLLHLAEDG VLSPLALTEG GKGSSPSIRP IQGSQGSSSP VEKEVVEATD SREKTGMVRP 600
GEPLSGEKYS PKELLALLKC VEAEIANYEA CLKEEVEKRK KFKIDDQRRT HNYDEFICTF 660
ISMLAQEGML ANLVEQNISV RRRQGVSIGR LHKQRKPDRR KRSRPYKAKR Q 711 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR001578; Peptidase_C12. 
Pfam
 PF01088; Peptidase_C12 
SMART
  
PROSITE
  
PRINTS
 PR00707; UBCTHYDRLASE.