CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044989
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ectopic P granules protein 5 homolog 
Protein Synonyms/Alias
  
Gene Name
 EPG5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
154KKAQTQLKLPIVPSLubiquitination[1]
225PAHINLLKEMKRRLTubiquitination[2]
243DFHHAASKALRVPAEubiquitination[1, 3]
368FTDPLLAKERVLSNLubiquitination[2]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 657 AA 
Protein Sequence
MIQAHISVST QPNEVGPVAV LEFWVQALIS QHLWYREQPI LFLMDHLCKA AFQLMQEDCI 60
QKLLYQQHKN ALGYHCDRSL LSSLVSWIVA GNITPSFVEG LATPTQVWFA WTVLNMESIF 120
EEDSQLRRVI EGELVINSAF TPDQALKKAQ TQLKLPIVPS LQRLLIYRWA HQALVTPSDH 180
PLLPLIWQKF FLLYLHRPGP QYGLPIDGCI GRRFFQSPAH INLLKEMKRR LTEVADFHHA 240
ASKALRVPAE GSEGLPESHS GTPGYLTSPE LHKELVRLFN VYILWLEDEN FQKGDTYIPS 300
LPKHYDIHRL AKVMQNQQDL WMEYLNMERI YHEFQETVGL WTQAKLESHS TPCSLSVQLD 360
FTDPLLAKER VLSNLRKHEA PQPPLALHPT KPPVPVISSA VLLSQKDATQ LVCTDLNLLQ 420
QQARTAALRE SQQVALDGEL LDTMPKQYVN REEQTTLHLE CRGSSGKKCQ GAAVVTVQFE 480
GMHKNEAISQ QLHVLRKEVK QLQAEAAKPP SLNIVEAAVH AENLITALVN AYKLQPTPGI 540
QKVGISLFFT IVDYVSDETQ RHPPTRQFFT SCIEILGQVF ISGIKSECRK VLETILKNSR 600
LCSLLSPFFT PNAAPAEFIQ LYEQVVKFLS EDNSDMIFML LTKASGVHSL GTYCLGP 657 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS