CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019873
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pyridoxal-dependent decarboxylase domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Pdxdc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
406PASDSAFKAVPVSNIubiquitination[1]
536NDDDTSLKSDPEGEKubiquitination[1]
551IHTGLLKKLNELESDubiquitination[1]
562LESDLTFKIGPEYKSubiquitination[1]
626EAQVQLQKANEERLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 MOD_RES 212 212 Phosphoserine.
 MOD_RES 652 652 Phosphoserine (By similarity).
 MOD_RES 687 687 Phosphothreonine.
 MOD_RES 691 691 Phosphothreonine (By similarity).
 MOD_RES 710 710 Phosphoserine (By similarity).
 MOD_RES 718 718 Phosphoserine.
 MOD_RES 722 722 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Decarboxylase; Lyase; Phosphoprotein; Pyridoxal phosphate; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 787 AA 
Protein Sequence
MDASLEKIAD PTLAEMGKNL KEAMRMLEKS PRRTEEENGK KPVSEDIPGP LQGSGQDMVS 60
ILQLVQNLMH GDEDEEPQST RIQNIGEQGH MALLGHSLGA YISTLDKEKL RKLTTRILSD 120
TTLWLRRIFR YENGCAYFHE EEREGLAKIC RLAIHSRYED FVVDGFNVLY NKKPVIYLSA 180
AARPGLGQYL CNQLGLPFPC LCRVPCNTMF GSQHQMDVAF LEKLIKDDVE RGRLPLLLVA 240
NAGTAAVGHT DKIGRLKELC EQYGIWLHVE GVNLATLALG YVSSSVLAAT KCDSMTLTPG 300
LWLGLPAVPA VTLYKHDDPA LTLVAGLTSN KPADKLRALP LWLSLQYLGL DGIVERIKHA 360
CHLSQRLQES LKKVDHIKIL VEDELSSPVV VFRFFQELPA SDSAFKAVPV SNIAPAAVGR 420
ERHSCDALNR WLGEQLKQLV PQCGLTVIDL EVDGTCVRFS PLMTAEGLGT RGEDVDQLIT 480
CIQSKLPVLT CTLQLREEFK QEVEGTAGLL YVDDPNWPGI GVVRYEHAND DDTSLKSDPE 540
GEKIHTGLLK KLNELESDLT FKIGPEYKSM KSCIYIGMAS DDVDVSELVE TIAVTAREIE 600
ENSRLLENMT EVVRKGIQEA QVQLQKANEE RLLEEGVLRQ IPVVGSVLNW FSPVQASQKG 660
RSFNLTAGSL ESTEYTYVHK VQGTGVTPPP TPLGTRSKQR LPGQKPFKRS LRGSDAVSET 720
SSVSHIEDLE KVEQLSSGLE HDNLEAHSPE QPPRATDLTA RQTEALQNQA QHQEDDHSQV 780
EELERLR 787 
Gene Ontology
 GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro. 
Interpro
 IPR002129; PyrdxlP-dep_de-COase.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF00282; Pyridoxal_deC 
SMART
  
PROSITE
 PS00392; DDC_GAD_HDC_YDC 
PRINTS