| Tag | Content |
|---|
| CPLM ID | CPLM-011178 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | U3 small nucleolar RNA-associated protein 15 |
Protein Synonyms/Alias | U3 snoRNA-associated protein 15; U three protein 15; U3 protein 15 required for transcription; t-UTP15 |
Gene Name | UTP15 |
Gene Synonyms/Alias | YMR093W; YM9582.18 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 81 | IKTFSRFKDVVYSAS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). |
Sequence Annotation | REPEAT 37 78 WD 1.
REPEAT 79 118 WD 2.
REPEAT 124 162 WD 3.
REPEAT 166 206 WD 4.
REPEAT 210 247 WD 5.
REPEAT 250 294 WD 6. |
Keyword | Complete proteome; Nucleus; Reference proteome; Repeat; Ribonucleoprotein; Ribosome biogenesis; rRNA processing; Transcription; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 513 AA |
Protein Sequence | MSTARPRIIT SKAPLLPQQT TPEQRYWRQY TSAQLVKEHN SVTHISFNPQ HPHDFAVTSS 60
TRVQIFSSRT RQVIKTFSRF KDVVYSASFR SDGKLLCAGD ATGLVSVYDS YNPRTILLSI 120
NASTHPTHVT KFHTQDNKIL ATASDDRVTR LWDISNAYEP QLELTGATDY VRTLSFIPAA 180
PHLVATGSYD GLIRLYDTRS SGSTPIYSLN HDQPVENVIA VSPTQIVSCG GNNFKVWDLT 240
SNKKLYERGN FNKAVTCLDY VENFDSPMQS ALIASSLDGH VKVFDPLDNF QVKFGWKFSG 300
PVLSCAVSPS TAQGNRHLVA GLSSGLLAIR TKKKEKRSSD KENAPASFNK NAKSNNFQRM 360
MRGSEYQGDQ EHIIHNDKVR SQRRMRAFER NINQFKWSEA LDNAFVPGMA KELTLTVLQE 420
LRKRGKVRVA LYGRDESTLE PLLNWCLKGI EDVRSASIVA DWVAVVLELY GNTLESSPVL 480
QELMIDLKTK VRHEIHKSKE AQRIEGMLQL LTS 513 |
Gene Ontology | GO:0033553; C:rDNA heterochromatin; IDA:SGD. GO:0032040; C:small-subunit processome; IDA:SGD. GO:0034455; C:t-UTP complex; IDA:SGD. GO:0030515; F:snoRNA binding; IPI:SGD. GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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