CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026478
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanine nucleotide binding protein, alpha stimulating, olfactory type 
Protein Synonyms/Alias
 Guanine nucleotide-binding protein G(olf) subunit alpha 
Gene Name
 Gnal 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
205QEFFDHVKKLWDDEGubiquitination[1]
206EFFDHVKKLWDDEGVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 448 AA 
Protein Sequence
MGLCYSLRPL LFGSPEDTPC AASEPCAEDA QPSAAPAPAS IPAPAPVGTL LRRGGGRIVA 60
NARPPGELQS RRRQEQLRAE EREAAKEARK VSRGIDRMLR EQKRDLQQTH RLLLLGAGES 120
GKSTIVKQMR ILHVNGFNPE EKKQKILDIR KNVKDAIVTI VSAMSTIIPP VPLANPENQF 180
RSDYIKSIAP ITDFEYSQEF FDHVKKLWDD EGVKACFERS NEYQLIDCAQ YFLERIDSVS 240
LVDYTPTDQD LLRCRVLTSG IFETRFQVDK VNFHMFDVGG QRDERRKWIQ CFNDVTAIIY 300
VAACSSYNMV IREDNNTNRL RESLDLFESI WNNRWLRTIS IILFLNKQDM LAEKVLAGKS 360
KIEDYFPEYA NYTVPEDATP DAGEDPKVTR AKFFIRDLFL RISTATGDGK HYCYPHFTCA 420
VDTENIRRVF NDCRDIIQRM HLKQYELL 448 
Gene Ontology
 GO:0005834; C:heterotrimeric G-protein complex; ISA:MGI.
 GO:0004016; F:adenylate cyclase activity; IBA:RefGenome.
 GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
 GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; ISA:MGI.
 GO:0004871; F:signal transducer activity; IBA:RefGenome.
 GO:0007190; P:activation of adenylate cyclase activity; IDA:MGI.
 GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IGI:MGI.
 GO:0001975; P:response to amphetamine; IMP:MGI.
 GO:0031000; P:response to caffeine; IMP:MGI.
 GO:0007608; P:sensory perception of smell; IMP:MGI. 
Interpro
 IPR000367; Gprotein_alpha_S.
 IPR001019; Gprotein_alpha_su.
 IPR011025; GproteinA_insert.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00503; G-alpha 
SMART
 SM00275; G_alpha 
PROSITE
  
PRINTS
 PR00318; GPROTEINA.
 PR00443; GPROTEINAS.