UniProt Accession

 E7EN86_HUMAN; E7EN86 

Genbank Protein ID

 AC127030; AC132192 

Genbank Nucleotide ID

  

Protein Name

 Zinc finger protein 143 

Protein Synonyms/Alias

  

Gene Name

 ZNF143 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
218	CEYDGCGKLYTTAHH	ubiquitination	[1]
227	YTTAHHLKVHERSHT	ubiquitination	[1, 2]
248	CEHAGCGKAFATGYG	ubiquitination	[1]
257	FATGYGLKSHVRTHT	ubiquitination	[1, 3]
278	CSEDNCTKSFKTSGD	ubiquitination	[1]
300	HTGERPFKCPFEGCG	ubiquitination	[1]
347	FASATNYKNHVRIHT	ubiquitination	[1, 2]
357	VRIHTGEKPYVCTVP	ubiquitination	[1]
368	CTVPGCDKRFTEYSS	ubiquitination	[1]
408	ISTLAMHKRTAHNDT	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 610 AA 

Protein Sequence

Gene Ontology

 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 

Pfam

 PF00096; zf-C2H2 

SMART

 SM00355; ZnF_C2H2 

PROSITE

 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 

PRINTS