CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024709
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Coiled-coil domain-containing protein 6 
Protein Synonyms/Alias
  
Gene Name
 Ccdc6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
74KIELETYKLKCKALQacetylation[1]
120IQALQKEKETLAVNYubiquitination[2]
166EQEFQVNKLMKKIKKubiquitination[2]
259MRHIRFLKNEVERLKubiquitination[2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 REPEAT 99 127 1.
 REPEAT 128 156 2.
 REPEAT 157 185 3.
 REPEAT 186 199 4; approximate.
 REPEAT 200 228 5.
 REGION 99 228 5 X 29 AA tandem repeats.
 MOTIF 435 444 SH3-binding (Potential).
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 45 45 Phosphoserine (By similarity).
 MOD_RES 233 233 Phosphoserine (By similarity).
 MOD_RES 237 237 Phosphoserine (By similarity).
 MOD_RES 242 242 Phosphoserine (By similarity).
 MOD_RES 247 247 Phosphoserine (By similarity).
 MOD_RES 277 277 Phosphoserine (By similarity).
 MOD_RES 316 316 Phosphoserine (By similarity).
 MOD_RES 318 318 Phosphoserine (By similarity).
 MOD_RES 342 342 Phosphothreonine (By similarity).
 MOD_RES 356 356 Phosphoserine (By similarity).
 MOD_RES 360 360 Phosphoserine (By similarity).  
Keyword
 Acetylation; Chromosomal rearrangement; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome; Repeat; SH3-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 469 AA 
Protein Sequence
MADSASESDT DAAGGGPAAM QSSCSATSGG SGGGGGGKSG GIVISPFRLE ELTNRLASLQ 60
QENKVLKIEL ETYKLKCKAL QEENRDLRKA SVTIQARAEQ EEEFISNTLF KKIQALQKEK 120
ETLAVNYEKE EEFLTNELSR KLMQLQHEKA ELEQHLEQEQ EFQVNKLMKK IKKLENDTIS 180
KQLTLEQLRR EKIDLENTLE QEQEALVNRL WKRMDKLEAE KRILQEKLDQ PVSAPPSPRD 240
ISMEIDSPEN MMRHIRFLKN EVERLKKQLR AAQLQHSEKM AQYLEEERHM REENLRLQRK 300
LQREMERREA LCRQLSESES SLEMDDERYF NEMSAQGLRP RTVSSPIPYT PSPSSSRPIS 360
PGLSYASHTV GFTPPTSLTR AGMSYYNSPG LHVQHMGASH GITRPSPRRS SSPDKFKRPT 420
PPPSPNTQSP VQPPPPPPPP PMQPAVPSAA PTQPAPTQPQ HPVHPSSQP 469 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. 
Interpro
 IPR019152; DUF2046. 
Pfam
 PF09755; DUF2046 
SMART
  
PROSITE
  
PRINTS