CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035265
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Appl1 
Protein Synonyms/Alias
  
Gene Name
 Appl1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
46AATHLTSKLLKEYEKacetylation[1]
49HLTSKLLKEYEKQRFacetylation[1]
107QFKERDLKEILTLKEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 690 AA 
Protein Sequence
QTRSLLGVFE EDATAISNYM NQLYQAMHRI YDAQNELSAA THLTSKLLKE YEKQRFPLGG 60
DDEVMSSTLQ QFSKVIDELS SCHAVLSTQL ADAMMFPISQ FKERDLKEIL TLKEVFQIAS 120
NDHDAAINRY SRLSKKREND KVKYEVTEDV YTSRKKQHQT MMHYFCALNT LQYKKKIALL 180
EPLLGYMQAQ ISFFKMGSEN LNGQLEEFLA NIGTSVQNVR REMDGDVETM QQTIEDLEVA 240
SDPLYLPDPD PTKFPVNRNL TRKAGYLNAR NKTGLVSSTW DRQFYFTQGG NLMSQARGDV 300
AGGLAMDIDN CSVMAVDCED RRYCFQITSF DGKKSSILQA ESKKDHEEWI CTINNISKQI 360
YLSENPEETA ARVNQSALEA VTPSPSFQQR HESLRPGGQS RPPTARTSSS GSLGSESTNL 420
AALSLDSLVA PDTPIQFDII SPVCEDQPGQ AKAFGQGGRR TNPFGESGGS TKSETEDSIL 480
HQLFIVRFLG SMEVKSDDHP DVVYETMRQI LAARAIHNIF RMTESHLLVT CDCLKLIDPQ 540
TQVTRLTFPL PYVVLYATHQ ENKRLFGFVL RTSGGRSESN LSSVCYIFES NNEGEKICDS 600
VGLAKQIALH AELDRRASEK QKEIERVKEK QQKELSKQKE IEKDLEEQSR LIAASSRPSQ 660
SGSEGQLVLS SSQSEESDLG EEGKKRESEA 690 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0010008; C:endosome membrane; IEA:Compara.
 GO:0016581; C:NuRD complex; IEA:Compara.
 GO:0012506; C:vesicle membrane; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0008283; P:cell proliferation; IEA:Compara.
 GO:0090003; P:regulation of establishment of protein localization to plasma membrane; IEA:Compara.
 GO:0046324; P:regulation of glucose import; IEA:Compara. 
Interpro
 IPR027267; AH/BAR-dom.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR006020; PTyr_interaction_dom. 
Pfam
 PF00640; PID 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN
 PS01179; PID 
PRINTS