CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031150
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptobrevin homolog YKT6 
Protein Synonyms/Alias
 cDNA FLJ50174, highly similar to Homo sapiens SNARE protein Ykt6 (YKT6), mRNA 
Gene Name
 YKT6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
15VLYKGEAKVVLLKAAacetylation[1]
103KVLDEFSKQVDRIDWacetylation[1]
103KVLDEFSKQVDRIDWubiquitination[2, 3]
141READPMTKVQAELDEubiquitination[3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 164 AA 
Protein Sequence
MKLYSLSVLY KGEAKVVLLK AAYDVSSFSF FQRSSVQEFM TFTSQLIVER SSKGTRASVK 60
EQDYLCHVYV RNDSLAGVVI ADNEYPSRVA FTLLEKVLDE FSKQVDRIDW PVGSPATIHY 120
PALDGHLSRY QNPREADPMT KVQAELDETK IILARKQNSC CAIM 164 
Gene Ontology
 GO:0016020; C:membrane; IEA:UniProtKB-KW.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR011012; Longin-like_dom.
 IPR010908; Longin_dom. 
Pfam
 PF13774; Longin 
SMART
  
PROSITE
 PS50859; LONGIN 
PRINTS