UniProt Accession

 M0R1L2_HUMAN; M0R1L2 

Genbank Protein ID

 AC010618 

Genbank Nucleotide ID

  

Protein Name

 6-phosphogluconolactonase 

Protein Synonyms/Alias

  

Gene Name

 PGLS 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
64	EAAEDYAKKLRQAFQ	ubiquitination	[1]
143	LLTVPFEKHSTL***	ubiquitination	[2, 3]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 147 AA 

Protein Sequence

Gene Ontology

 GO:0017057; F:6-phosphogluconolactonase activity; IEA:InterPro.
 GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. 

Interpro

 IPR005900; 6-phosphogluconolactonase_DevB.
 IPR006148; Glc/Gal-6P_isomerase. 

Pfam

 PF01182; Glucosamine_iso 

SMART

  

PROSITE

  

PRINTS