CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036141
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tetratricopeptide repeat protein 37 
Protein Synonyms/Alias
  
Gene Name
 TTC37 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
66YESVDKQKWCDVCKKubiquitination[1]
286LSCSQALKIVDNLGAubiquitination[1]
344IPGLLVLKSLAYRNKubiquitination[1, 2]
393KDYLQAEKCFQRALEubiquitination[1]
548AALRADPKDFNCWESubiquitination[1]
571GGYTTALKSFTKASEubiquitination[3]
599AIQQILGKYKEAVAQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 611 AA 
Protein Sequence
MSSKEVKTAL KSARDAIRNK EYKEALKHCK GLANLYEKYN HINAKDDLPG VYQKLLDLYE 60
SVDKQKWCDV CKKLVDLYYQ EKKHLEVART WHKLIKTRQE QGAENEELHQ LWRKLTQFLA 120
ESTEDQNNET QQLLFTAFEN ALGLSDKIPS EDHQVLYRHF IQSLSKFPHE SARLKKACEG 180
MINIYPTVQY PLEVLCLHLI ESGNLTDEGQ QYCCRLVEMD SKSGPGLIGL GIKALQDKKY 240
EDAVRNLTEG LKESPVCTSG WYHLAEAQVK MHRPKEAVLS CSQALKIVDN LGASGNSLYQ 300
RNLCLHLKAE ALIKLSDYDS SEEAIRTLDQ ISDADNIPGL LVLKSLAYRN KGSFDEAAKI 360
MEDLLSSYPD LAEVHALEAL IHFTKKDYLQ AEKCFQRALE KDTEVAEYHY QLGLTYWFMG 420
EETRKDKTKA LTHFLKAARL DTYMGKVFCY LGHYYRDVVG DKNRARGCYR KAFELDDTDA 480
ESGAAAVDLS VELEDMEMAL AILTTVTQKA SAGTAKWAWL RRGLYYLKAG QHSQAVADLQ 540
AALRADPKDF NCWESLGEAY LSRGGYTTAL KSFTKASELN PESIYSVFKV AAIQQILGKY 600
KEAVAQYQMI I 611 
Gene Ontology
  
Interpro
 IPR006597; Sel1-like.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF08238; Sel1
 PF13174; TPR_6 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS