UniProt Accession

 HPCL4_RAT; P35332 

Genbank Protein ID

 D13125 

Genbank Nucleotide ID

 BAA02427.1 

Protein Name

 Hippocalcin-like protein 4 

Protein Synonyms/Alias

 Neural visinin-like protein 2; NVL-2; NVP-2; Visinin-like protein 2; VILIP-2 

Gene Name

 Hpcal4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
74	HAFRTFDKNGDGTID	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. 

Sequence Annotation

 DOMAIN 24 59 EF-hand 1.
 DOMAIN 60 95 EF-hand 2.
 DOMAIN 96 131 EF-hand 3.
 DOMAIN 146 181 EF-hand 4.
 LIPID 2 2 N-myristoyl glycine (By similarity).  

Keyword

 Calcium; Complete proteome; Lipoprotein; Metal-binding; Myristate; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 191 AA 

Protein Sequence

Gene Ontology

 GO:0005622; C:intracellular; IEA:Compara.
 GO:0005246; F:calcium channel regulator activity; IDA:RGD.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR001125; Recoverin. 

Pfam

 PF13499; EF_hand_5
 PF00036; efhand 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS

 PR00450; RECOVERIN.