CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044566
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Abhydrolase domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 ABHD3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
55YLSSIAKKPQLVTGGubiquitination[1]
102LRPFITSKPPVQYRNubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MQRLAMDLRM LSRELSLYLE HQVRVGFFGS GVGLSLILGF SVAYAFYYLS SIAKKPQLVT 60
GGESFSRFLQ DHCPVVTETY YPTVWCWEGR GQTLLRPFIT SKPPVQYRNE LIKTADGGQI 120
SLDWFDNDNS TCYMDASTRP TILLLPGLTG TSKESYILHM IHLSEELGYR MLLLNYLGKI 180
GSKTPLMAAA TFSVGWNTFA CSESLEKPLN WLLFNYYLTT CLQSSVNKHR HMFVKQVDMD 240
HVMKAKSIRE FDKRFTSVMF GYQTIDDYYT DASPSPRLKS VGIPVLCLNS VDDVFSPSHA 300
IPIETAKQNP NVALVLTSYG GHIGFLEGIW PRQSTYMDRV FKQFVQAMVE HGHELS 356 
Gene Ontology
 GO:0004091; F:carboxylesterase activity; IEA:InterPro. 
Interpro
 IPR012020; AB-Hydro_YheT.
 IPR000952; UPF0017_hydro-like_CS. 
Pfam
  
SMART
  
PROSITE
 PS01133; UPF0017 
PRINTS