CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010353
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized HTH-type transcriptional regulator YdcR 
Protein Synonyms/Alias
  
Gene Name
 ydcR 
Gene Synonyms/Alias
 b1439; JW1434 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
458EREEQAVKQLGKLIQacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 69 HTH gntR-type.
 MOD_RES 312 312 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Aminotransferase; Complete proteome; DNA-binding; Pyridoxal phosphate; Reference proteome; Transcription; Transcription regulation; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 468 AA 
Protein Sequence
MKKYQQLAEQ LREQIASGIW QPGDRLPSLR DQVALSGMSF MTVSHAYQLL ESQGYIIARP 60
QSGYYVAPQA IKMPKAPVIP VTRDEAVDIN TYIFDMLQAS RDPSVVPFAS AFPDPRLFPL 120
QQLNRSLAQV SKTATAMSVI ENLPPGNAEL RQAIARRYAL QGITISPDEI VITAGALEAL 180
NLSLQAVTEP GDWVIVENPC FYGALQALER LRLKALSVAT DVKEGIDLQA LELALQEYPV 240
KACWLMTNSQ NPLGFTLTPQ KKAQLVALLN QYNVTLIEDD VYSELYFGRE KPLPAKAWDR 300
HDGVLHCSSF SKCLVPGFRI GWVAAGKHAR KIQRLQLMST LSTSSPMQLA LVDYLSTRRY 360
DAHLRRLRRQ LAERKQRAWQ ALLRYLPAEV KIHHNDSGYF LWLELPEPLD AGELSLAALT 420
HHISIAPGKM FSTGENWSRF FRFNTAWQWG EREEQAVKQL GKLIQERL 468 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR000524; Tscrpt_reg_HTH_GntR.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00155; Aminotran_1_2
 PF00392; GntR 
SMART
 SM00345; HTH_GNTR 
PROSITE
 PS50949; HTH_GNTR 
PRINTS