UniProt Accession

 A2AWE9_MOUSE; A2AWE9 

Genbank Protein ID

 AL954299 

Genbank Nucleotide ID

  

Protein Name

 Serine/threonine-protein phosphatase 2A activator 

Protein Synonyms/Alias

  

Gene Name

 Ppp2r4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
244	SAVPSWSKVNQGLIR	acetylation	[1]
254	QGLIRMYKAECLEKF	acetylation	[2]
260	YKAECLEKFPVIQHF	acetylation	[2]

Reference

 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 281 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0005634; C:nucleus; IBA:RefGenome.
 GO:0000159; C:protein phosphatase type 2A complex; IBA:RefGenome.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
 GO:0008601; F:protein phosphatase type 2A regulator activity; IBA:RefGenome.
 GO:0008160; F:protein tyrosine phosphatase activator activity; IBA:RefGenome.
 GO:0030472; P:mitotic spindle organization in nucleus; IBA:RefGenome. 

Interpro

 IPR004327; Phstyr_phstse_ac. 

Pfam

 PF03095; PTPA 

SMART

  

PROSITE

  

PRINTS