| Tag | Content |
|---|
| CPLM ID | CPLM-030321 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
Protein Synonyms/Alias | Protein Abcc8 |
Gene Name | Abcc8 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 205 | FKTPREVKPPEDLQD | ubiquitination | [1] | | 252 | IDLRAIGKLPIAMRA | ubiquitination | [1] | | 954 | KETVMERKAPEPSQG | ubiquitination | [1] | | 1365 | VRYDSSLKPVLKHVN | ubiquitination | [1] | | 1576 | PEKLLSQKDSVFASF | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1588 AA |
Protein Sequence | MPLAFCGTEN HSAAYRVDQG VLNNGCFVDA LNVVPHVFLL FITFPILFIG WGSQSSKVHI 60
HHSTWLHFPG HNLRWILTFM LLFVLVCEIA EGILSDGVTE SRHLHLYMPA GMAFMAAITS 120
VVYYHNIETS NFPKLLIALL IYWTLAFITK TIKFVKFYDH AIGFSQLRFC LTGLLVILYG 180
MLLLVEINVI RVRRYIFFKT PREVKPPEDL QDLGVRFLQP FVNLLSKGTY WWMNAFIKTA 240
HRKPIDLRAI GKLPIAMRAL TNYQRLCAAF DAQARKDTQS QQGARAIWRA LCHAFGRRLV 300
LSSTFRILAD LLGFAGPLCI FGIVDHLGKE NHVFQPKTQF LGVYFVSSQE FLGNAYVLAV 360
LLFLALLLQR TFLQASYYVA IETGINLRGA IQTKIYNKIM HLSTSNLSMG EMTAGQICNL 420
VAIDTNQLMW FFFLCPNLWA MPVQIIVGVI LLYYILGVSA LIGAAVIILL APVQYFVATK 480
LSQAQRSTLE YSNERLKQTN EMLRGIKLLK LYAWENIFCS RVEMTRRKEM TSLRAFAVYT 540
SISIFMNTAI PIAAVLITFV GHVSFFKESD FSPSVAFASL SLFHILVTPL FLLSSVVRST 600
VKALVSVQKL SEFLSSAEIR EEQCAPREPA PQGQAGKYQA VPLKVVNRKR PAREEVRDLL 660
GPLQRLTPSM DGDADNFCVQ IIGGFFTWTP DGIPTLSNIT IRIPRGQLTM IVGQVGCGKS 720
SLLLATLGEM QRVSGAVFWN SSLPDSEGED PRYCLRTSNP ERETAADSDA RSRGPVAYAS 780
QKPWLLNATV EENITFESPF NKQRYKMVIE ACSLQPDIDI LPHGDQTQIG ERGINLSGGQ 840
RQRISVARAL YQHTNVVFLD DPFSALDVHL SDHLMQAGIL ELLRDDKRTV VLVTHKLQYL 900
PHADWIIAMK DGTIQREGTL KDFQRSECQL FEHWKTLMNR QDQELEKETV MERKAPEPSQ 960
GLPRAMSSRD GLLLDEDEEE EEAAESEEDD NLSSVLHQRA KIPWRACTKY LSSAGVLLLS 1020
LLVFSQLLKH MVLVAIDYWL AKWTDSALVL SPAARNCSLS QECALDQSVY AMVFTVLCSL 1080
GIALCLVTSV TVEWTGLKVA KRLHRSLLNR IILAPMRFFE TTPLGSILNR FSSDCNTIDQ 1140
HIPSTLECLS RSTLLCVSAL TVISYVTPVF LVALLPLAVV CYFIQKYFRV ASRDLQQLDD 1200
TTQLPLLSHF AETVEGLTTI RAFRYEARFQ QKLLEYTDSN NIASLFLTAA NRWLEVRMEY 1260
IGACVVLIAA ATSISNSLHR ELSAGLVGLG LTYALMVSNY LNWMVRNLAD MEIQLGAVKR 1320
IHTLLKTEAE SYEGLLAPSL IPKNWPDQGK IQIQNLSVRY DSSLKPVLKH VNALIAPGQK 1380
IGICGRTGSG KSSFSLAFFR MVDMFEGRII IDGIDIAKLP LHTLRSRLSI ILQDPVLFSG 1440
TIRFNLDPEK KCSDSTLWEA LEIAQLKLVV KALPGGLDAI ITEGGENFSQ GQRQLFCLAR 1500
AFVRKTSIFI MDEATASIDM ATENILQKVV MTAFADRTVV TIAHRVHTIL SADLVMVLKR 1560
GAILEFDKPE KLLSQKDSVF ASFVRADK 1588 |
Gene Ontology | GO:0005886; C:plasma membrane; IDA:MGI. GO:0008076; C:voltage-gated potassium channel complex; IEA:Compara. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro. GO:0008281; F:sulfonylurea receptor activity; IEA:InterPro. GO:0006200; P:ATP catabolic process; IEA:GOC. GO:0006813; P:potassium ion transport; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |