CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029433
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HCG40298, isoform CRA_d 
Protein Synonyms/Alias
 Phosphatidylinositol-glycan biosynthesis class X protein 
Gene Name
 PIGX 
Gene Synonyms/Alias
 hCG_40298 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
13ILRQEVLKDGFHRDLubiquitination[1]
25RDLLIKVKFGESIEDubiquitination[1]
41HTCRLLIKQDIPAGLubiquitination[1, 2, 3, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 217 AA 
Protein Sequence
MCSEIILRQE VLKDGFHRDL LIKVKFGESI EDLHTCRLLI KQDIPAGLYV DPYELASLRE 60
RNITEAVMVS ENFDIEAPNY LSKESEVLIY ARRDSQCIDC FQAFLPVHCR YHRPHSEDGE 120
ASIVVNNPDL LMFCDQEFPI LKCWAHSEVA APCALENEDI CQWNKMKYKS VYKNVILQVP 180
VGLTVHTSLV CSVTLLITIL CSTLILVAVF KYGHFSL 217 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
 GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro. 
Interpro
 IPR013233; PIG-X/PBN1. 
Pfam
 PF08320; PIG-X 
SMART
 SM00780; PIG-X 
PROSITE
  
PRINTS