CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018161
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium- and chloride-dependent transporter XTRP3A 
Protein Synonyms/Alias
 IMINO-B; Solute carrier family 6 member 20A; X transporter protein 3 similar 1 
Gene Name
 Slc6a20a 
Gene Synonyms/Alias
 Slc6a20; Xt3s1; Xtm3s1; Xtrp3s1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
347LASTYPNKYSEVFPHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids. 
Sequence Annotation
 CARBOHYD 131 131 N-linked (GlcNAc...) (Potential).  
Keyword
 Amino-acid transport; Cell membrane; Complete proteome; Glycoprotein; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 592 AA 
Protein Sequence
MEKARPQWGH PLQFVFACIS YAVGLGNVWR FPYLCQMYGG GSFLVPYIIM LIVEGMPLLY 60
LELAVGQRMR QGSIGAWRTI SPYLSGVGVA SVVVSFFLSM YYNVINAWGF WYLFHSFQDP 120
LPWSVCPLNS NHTGYDEECE KASSTQYFWY RKTLNISPSI QENGGVQWEP ALCLTLAWLM 180
VYLCILRGTE STGKVVYFTA SMPYCVLIIY LVRGLTLHGA TNGLMYMFTP KMEQLANPKA 240
WINAATQIFF SLGLGFGSLI AFASYNEPSN NCQKHAIIVS IINSSTSIFA SIVTFSIYGF 300
KATFNYENCL NKVILLLTNS FDLEDGFLTV SNLEEVKNYL ASTYPNKYSE VFPHIRNCSL 360
ESELDTAVQG TGLAFIVYTE AIKNMEVSQL WSVLYFFMLL MLGIGSMLGN TAAILTPLTD 420
SKVISSYLPK EAISGLVCLI NCAVGMVFTM EAGNYWFDIF NDYAATLSLL LIVLVETIAV 480
CYVYGLKRFE SDLRAMTGRT LSWYWKVMWA FVSPLLIVGL FIFYLSDYIL TGTLQYQAWD 540
ATQGQLVTKD YPPHALAVIG LLVASSTMCI PLVALGTFIR NRLKRGGSAP VA 592 
Gene Ontology
 GO:0016324; C:apical plasma membrane; IDA:UniProtKB.
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0015171; F:amino acid transmembrane transporter activity; IDA:UniProtKB.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
 GO:0015816; P:glycine transport; IEA:Compara.
 GO:0015824; P:proline transport; IEA:Compara. 
Interpro
 IPR000175; Na/ntran_symport.
 IPR002438; Na/ntran_symport_orphan. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00610; NA_NEUROTRAN_SYMP_1
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR00176; NANEUSMPORT.
 PR01206; ORPHTRNSPORT.