CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014453
UniProt Accession
Genbank Protein ID
 U17133 
Genbank Nucleotide ID
Protein Name
 Zinc transporter 1 
Protein Synonyms/Alias
 ZnT-1; Solute carrier family 30 member 1 
Gene Name
 Slc30a1 
Gene Synonyms/Alias
 Znt1 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
353VPKQIDIKHLVKELRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May be involved in zinc transport out of the cell. 
Sequence Annotation
 REGION 145 156 6 X 2 AA approximate repeats of H-G.
 MOD_RES 506 506 Phosphoserine (By similarity).
 CARBOHYD 298 298 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MGCWGRNRGR LLCMLLLTFM FMVLEVVVSR VTASLAMLSD SFHMLSDVLA LVVALVAERF 60
ARRTHATQKN TFGWIRAEVM GALVNAIFLT GLCFAILLEA VERFIEPHEM QQPLVVLSVG 120
VAGLLVNVLG LCLFHHHSGE GQGAGHGHSH GHGHGHLAKG ARKAGRAGGE AGAPPGRAPD 180
QEPDQEETNT LVANTSNSNG LKADQAEPEK LRSDDPVDVQ VNGNLIQESD SLESEDNRAG 240
QLNMRGVFLH VLGDALGSVI VVVNALVFYF SWKGCTEDDF CVNPCFPDPC KSSVELMNST 300
QAPMHEAGPC WVLYLDPTLC IIMVCILLYT TYPLLKESAL ILLQTVPKQI DIKHLVKELR 360
DVEGVEEVHE LHVWQLAGSR IIATAHIKCE DPASYMQVAK TIKDVFHNHG IHATTIQPEF 420
ASVGSKSSVV PCELACRTQC ALKQCCGTRP QVHSGKEAEK APTVSISCLE LSENLEKKPR 480
RTKAEGSVPA VVIEIKNVPN KQPESSL 507 
Gene Ontology
 GO:0016021; C:integral to membrane; IDA:RGD.
 GO:0030315; C:T-tubule; IDA:BHF-UCL.
 GO:0019855; F:calcium channel inhibitor activity; IMP:BHF-UCL.
 GO:0005385; F:zinc ion transmembrane transporter activity; IDA:MGI.
 GO:0070574; P:cadmium ion transmembrane transport; IMP:BHF-UCL.
 GO:0070509; P:calcium ion import; IMP:BHF-UCL.
 GO:0006874; P:cellular calcium ion homeostasis; IEA:Compara.
 GO:0006882; P:cellular zinc ion homeostasis; IEA:Compara.
 GO:0071585; P:detoxification of cadmium ion; IMP:BHF-UCL.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0090281; P:negative regulation of calcium ion import; IEA:Compara.
 GO:0046929; P:negative regulation of neurotransmitter secretion; IMP:BHF-UCL.
 GO:0071584; P:negative regulation of zinc ion transmembrane import; IEA:Compara. 
Interpro
 IPR002524; Cation_efflux.
 IPR027469; Cation_efflux_TMD. 
Pfam
 PF01545; Cation_efflux 
SMART
  
PROSITE
  
PRINTS