UniProt Accession

 XXLT1_HUMAN; Q8NBI6; D3DNW5; Q8NAL3; Q8WV03; Q96ME0 

Genbank Protein ID

 AK057046; AK092474; AK075551; CH471052; CH471052; BC019036; BC039067 

Genbank Nucleotide ID

 BAB71355.1; BAC03899.1; BAC11694.1; EAW78028.1; EAW78029.1; AAH19036.1; AAH39067.2 

Protein Name

 Xyloside xylosyltransferase 1 

Protein Synonyms/Alias

 UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase 

Gene Name

 XXYLT1 

Gene Synonyms/Alias

 C3orf21; PSEC0251 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
321	QVQQLADKYHFRGHL	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Alpha-1,3-xylosyltransferase, which elongates the O- linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of the second xylose. 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Endoplasmic reticulum; Glycosyltransferase; Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 393 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:EC. 

Interpro

 IPR002495; Glyco_trans_8. 

Pfam

 PF01501; Glyco_transf_8 

SMART

  

PROSITE

  

PRINTS